1,3,3-Trimethyl-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-1-ol
نویسندگان
چکیده
In the title compound, C(14)H(18)N(2)O, the benzimidazole grouping is close to planar, with a maximum deviation of 0.042 Å; the six-membered non-aromatic ring adopts an envelope conformation. In the crystal structure, mol-ecules are linked into infinite sheets lying parallel to the bc plane by O-H⋯N and C-H⋯O hydrogen bonds.
منابع مشابه
Antibacterial Effect of Ginger (Zingiber officinale) Roscoe and Bioactive Chemical Analysis using Gas Chromatography Mass Spectrum
The objectives of this research was to determine the chemical composition of roscoe extract from methanol and evaluation of antibacterial activity. The phytochemical compound screened by GC-MS method. Forty eight bioactive phytochemical compounds were identified in the methanolic extract of Zingiber officinale. The identification of phytochemical compounds is based on the peak area, retention t...
متن کامل4-Phenyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-2-one
In the title compound, C(16)H(13)N(3)O, the tetrahydropyrimidin-one ring adopts a sofa conformation. In the crystal structure, mol-ecules are linked by N-H⋯N hydrogen bonds and C-H⋯π inter-actions.
متن کاملVibrational spectroscopic study on 2-[2-(4-dipropylamino-phenyl)-vinyl]-1,3,3-trimethyl-3H-indolium chloride.
A new styryl dye were prepared, 2-[2-(4-dipropylamino-phenyl)-vinyl]-1,3,3-trimethyl-3H-indolium chloride (DPPTVI) chloride. Its infrared and Raman were measured. Quantum chemical calculations were computed for both the isolated and the solute cation. Optimized geometry, atomic net charges were calculated. The calculated vibrational frequencies were scaled to the experimental ones. Only 12 scal...
متن کاملBis{1-[(1H-benzimidazol-1-yl)methyl-κN 3]-1H-1,2,3,4-tetrazole}silver(I) nitrate
In the title salt, [Ag(C(9)H(8)N(6))(2)]NO(3), the central Ag(I) atom is linearly coordinated by the N atoms [171.97 (8)°] from two 1-[(benzimidazol-1-yl)meth-yl]-1H-1,2,3,4-tetra-zole ligands. The benzimidazole rings in adjacent mol-ecules are parallel with an average inter-planar distance of 3.461 Å; adjacent mol-ecules are linked through N-H⋯O hydrogen bonds into a linear chain along the b-a...
متن کاملSynthesis and multidrug resistance reversal activity of 1,2-disubstituted tetrahydroisoquinoline derivatives.
BACKGROUND Cancer treatment often fails due to multidrug resistance (MDR) of the tumor cells. One of the major causes is overexpression of P-glycoprotein (P-gp). MATERIALS AND METHODS By N-substitution reactions of diamine, amino acid and amino alcohol derivatives with 1-substituted tetrahydroisoquinoline skeleton, structurally diverse 1,2-disubstituted 1,2,3,4-tetrahydroisoquinolines were sy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010